REACTION OF SOME BENZOXAZOLINE-2-THIONE DERIVATIVES WITH AMINES

Article abstract of DOI:10.1007/BF00507240

Hydroxyphenylthioureas were obtained by the reaction of nitro, chloro, bromo, or amino derivatives of benzoxazoline-2-thiones with primary amines.If the substituent in the benzene ring is a nitro group, the reaction with certain secondary amines proceeds with the production of trisubstituted thioureas.It is shown that electron-acceptor substituents in the 5 and 6 positions of the benzene ring facilitate this reaction.