Journal of Medicinal Chemistry p. 1184 - 1191 (1981)
Update date:2022-07-29
Topics:
Hodges, John C.
Remers, William A.
Bradner, William T.
A series of 1-substituted mitosene analogues of the mitomycin antitumor antibiotics was prepared by total synthesis and screened for activity against P388 leukemia in mice.In general, analogues with moderately good leaving groups (mostly esters) at the 1
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Doi:10.1016/S0040-4039(01)93300-3
(1981)Doi:10.1021/j150614a028
(1981)Doi:10.1002/anie.201502041
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