Nucleotide. XV. Synthese und Eigenschaften von 2'-O-t-Butyldimethylsilyl-5'-O-monomethoxytritylribonucleosid-3'-phosphotriestern, Ausgangssubstanzen fuer Oligonucleotid-Synthesen

Article abstract of DOI:10.1002/hlca.19810640548

The syntheses of two types of fully blocked ribonucleoside 3'-phosphotriesters 6-14 have been achieved in excellent yields from 2'-O-t-butyldimethylsilyl-5'-O-monomethoxytrityl-ribonucleosides 1-5 by phosphorylation with 2-chloro- and 2,5-dichlorophenylph