The Formylation of an Aromatic Nucleus by the Use of 2-Ethoxy-1,3-dithiolane

Article abstract of DOI:10.1246/bcsj.54.2120

The reaction of various phenols with 2-ethoxy-1,3-dithiolane proceeded smoothly in the presence of BF3*Et2O to afford 1,3-dithiolan-2-ylated phenols, which were readily hydrolyzed to the corresponding aldehydes.This process was also extended to N,N-dimethylaniline and indole.