A CONVENIENT ONE-POT PROCEDURE FOR SYNTHESIS OF THIOL ESTERS USING MAGNESIUM ION AS A CATALYST

Article abstract of DOI:10.1016/S0040-4039(01)81874-8

Various thiol esters (R¹COSR²) were prepared in high yields by treatment of 1-acylimidazole with thiols in the presence of a catalytic amount of Mg(OEt)2.Malonic half-thiol esters 1OCOCH(R³)COSR²> were also prepared in good yields by treating magnesium monoalkyl malonate 1OCOCH(R³)COOMg0.5> with carbonyl-1,1'-diimidazole followed by addition of thiols.