Wittig Reactions with β-Lactam Carbonyls: A Convenient Means of Protection. X-Ray Crystal Structure of p-Nitrobenzyl-(2R,5R)-Z-7-Methoxycarbonylmethylene-Z-3-(β-phthalimidoethylidene)-4-oxa-1-azabicycloheptane-2-carboxylate

DOI: 10.1039/c39810000929

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 929 - 930 (1981)

Update date:2022-08-02

Topics:

Authors:

Gilpin, Martin L.

Harbridge, John B.

Howarth, T. Trefor

King, Trevor J.

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Article abstract of DOI:10.1039/c39810000929

Clavulanic acid derivatives and penicillin V esters undergo Wittig reactions at the β-lactam carbonyl and the β-lactam can be regenerated by low-temperature ozonolysis; the crystal structure of one of the products is reported.

Full text of DOI:10.1039/c39810000929

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