SRN1 Mechanism in Heteroaromatic Nucleophilic Substitution. Reactions of 2-Chloroquinoxaline and 4-Chloroquinazolines with Ketone Enolates

DOI: 10.1021/jo00345a028

Source and publish data:

Journal of Organic Chemistry p. 1036 - 1040 (1982)

Update date:2022-09-26

Topics:

Authors:

Carver, David R.

Hubbard, James S.

Wolfe, James F.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00345a028

Reaction of 2-chloroquinoxaline (1) with O-potassio-3,3-dimethyl-2-butanone (2) in liquid NH3 affords 1-(quinoxalin-2-yl)-3,3-dimethyl-2-butanone (3) via a thermal S_RN1 mechanism and 2-tert-butylfuro<2,3-b>quinoxaline (4) via a competing ionic,

Full text of DOI:10.1021/jo00345a028

Products guided by the article

Product name:quinoxalino<3,4-b>-2,2,5,5-tetramethylcyclopentanone

Cas No:80360-34-5

R&D Labs maybe for 80360-34-5

Shanghai Yingrui Biopharma Co., Ltd

Contact:021-3358 8661*8003

Address:shanghai
Ningbo Hi-tech Zone Nice-Synth Chemical Industry Ltd.

Contact:+86-(574)-81110986

Address:No. 1210, Building 3, Wante Business Centre, Hi-tech Zone, Ningbo
Hangzhou utanpharma Co., Ltd

Contact:86-571-87758773

Address:Room604 ,6F, Block A1-3 Xixi Plaza,No. 588 Wenyi West RD, Hangzhou,310012, China
Shanghai Dianyang Industry Co.,ltd

Contact:+86 21 6492 4669

Address:Chejing RD, Songjiang District, Shanghai, China
Beijing Green Guardee Technology CO,.LTD

Contact:+86-10-69706062

Address:F2 BLdj,5 No.37 Chaoqian Road

Relevant to this article

Doi:10.1021/ja01598a012
(1956)
Doi:10.1021/ja00855a043
(1975)
Enantiomerically Selective Pig Liver Esterase-catalysed Hydrolyses of Racemic Allenic Esters

Doi:10.1039/c39860001545
(1986)
The threo-Selective Reaction of Allenic Organometallic Compounds with Imines

Doi:10.1039/c39840001004
(1984)
Doi:10.1039/jr9610005532
(1961)
Doi:10.1002/hlca.19750580311
(1975)

Article Doi