SRN1 Mechanism in Heteroaromatic Nucleophilic Substitution. Reactions of 2-Chloroquinoxaline and 4-Chloroquinazolines with Ketone Enolates

DOI: 10.1021/jo00345a028

Source and publish data:

Journal of Organic Chemistry p. 1036 - 1040 (1982)

Update date:2022-09-26

Topics:

Authors:

Carver, David R.

Hubbard, James S.

Wolfe, James F.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00345a028

Reaction of 2-chloroquinoxaline (1) with O-potassio-3,3-dimethyl-2-butanone (2) in liquid NH3 affords 1-(quinoxalin-2-yl)-3,3-dimethyl-2-butanone (3) via a thermal S_RN1 mechanism and 2-tert-butylfuro<2,3-b>quinoxaline (4) via a competing ionic,

Full text of DOI:10.1021/jo00345a028

Products guided by the article

Product name:quinoxalino<3,4-b>-2,2,5,5-tetramethylcyclopentanone

Cas No:80360-34-5

R&D Labs maybe for 80360-34-5

Nantong LiKai Chemical Co.,Ltd

Contact:+86-513-89068669

Address:Jincheng Science Park
Changzhou Ansciep Chemical Co.,Ltd.

Contact:+86 519 8630 5871

Address:A-710 Boan International, 8 East Guangdian Road,Wujin,Changzhou
Hisyntech Corporation Limited

Contact:0086-22-23410962

Address:17-201, Ningfuli, Shuishanggongyuandong road,Nankai district, Tianjin, China
Hunan Zhongqi Pharmaceutical Co., Ltd

website:http://www.hnzqzy.com

Contact:0730-8722288 13807308622

Address:Wanjiafan Road ,Yueyang Economic And Technological Development Zone ,Hunan,PRC
TIANJIN DONGRUXIANG MINERALS MARKETING CO.,LTD(expird)

Contact:22-58516360

Address:tianjin

Relevant to this article

Doi:10.1021/ja01598a012
(1956)
Doi:10.1021/ja00855a043
(1975)
Enantiomerically Selective Pig Liver Esterase-catalysed Hydrolyses of Racemic Allenic Esters

Doi:10.1039/c39860001545
(1986)
The threo-Selective Reaction of Allenic Organometallic Compounds with Imines

Doi:10.1039/c39840001004
(1984)
Doi:10.1039/jr9610005532
(1961)
Doi:10.1002/hlca.19750580311
(1975)

Article Doi