THE 2-PHENYLSULFONYLETHYLCARBONYL (PSEC) GROUP FOR THE PROTECTION OF THE HYDROXYL FUNCTION

Article abstract of DOI:10.1016/S0040-4039(01)81988-2

The PSEC group may be used to protect the hydroxyl function in conjunction with a variety of acid and base labile protecting groups; the PSEC group may be removed by treatment of triethylamine (15 equiv.) in dry pyridine solution within 20 h at 20 deg C while other base labile protecting groups remained intact.