Whole Cell Catalysed Kinetic Resolution of 6-Azabicyclohept-3-en-7-one: Synthesis of (-)-Cispentacin (FR 109615)

DOI: 10.1039/P19910002276

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 2276 - 2277 (1991)

Update date:2022-08-04

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Authors:

Evans, Chris

McCague, Ray

Roberts, Stanley M.

Sutherland Alan G.

Wisdom, Richard

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Article abstract of DOI:10.1039/P19910002276

Enantioselective hydrolysis of the β-lactam (+/-)2 using Rhodococcus equi provided (1R,5S)-6-azabicyclo<3.2.0>hept-3-en-7-one (+)-2, a precursor of the antifungal agent cispentacin.

Full text of DOI:10.1039/P19910002276

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