Synthesis and Antiinflammatory Activity of cis- and trans-6,6a,7,8,9,10,10a,11-Octahydro-11-oxodibenzothiepinacetic and -oxepinacetic Acids

DOI: 10.1021/jm00164a006

Source and publish data:

Journal of Medicinal Chemistry p. 504 - 509 (1990)

Update date:2022-07-31

Topics:

Authors:

Kurokawa, Mikio

Uno, Hitoshi

Nakamura, Hideo

Sato, Fuminori

Naruto, Shunsuke

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Article abstract of DOI:10.1021/jm00164a006

A series of cis- and trans-6,6a,7,8,9,10,10a,11-octahydro-11-oxodibenzothiepinacetic acids (6-9) and -oxepinacetic acids (10-13) were prepared and their antiinflammatory activity was examined in the rat carrageenan hind paw edema test.The antiinflamm

Full text of DOI:10.1021/jm00164a006

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