Journal of Medicinal Chemistry p. 877 - 880 (1982)
Update date:2022-08-03
Topics:
Piper, J. R.
McCaleb, G. S.
Montgomery, J. A.
Kisliuk, R. L.
Gaumont, Y.
Sirotnak, F. M.
Reported antifolate activity against leukemia L1210 by N-<4-<<(2-amino-4-hydroxy-6-quinazolinyl)methyl>propargylamino>benzoyl>-L-glutamic acid through potent inhibition of thymidylate synthase (EC 2.1.1.45) prompted us to include the propargyl group in a
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Doi:10.1248/cpb.30.3160
(1982)Doi:10.1039/jr9380000008
(1938)Doi:10.1021/ja00381a057
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(1996)Doi:10.1134/S1070428013020127
(2013)Doi:10.1271/bbb.68.1961
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