N-Unsubstituted β-Lactams from β-Hydroxy-α-amino Acids. Facile Preparation of Intermediates for Isocephalosporins

DOI: 10.1021/jo00142a015

Source and publish data:

Journal of Organic Chemistry p. 4075 - 4081 (1982)

Update date:2022-08-05

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Authors:

Bose, Ajay K.

Manhas, M. S.

Vincent, J. E.

Gala, K.

Fernandez, I. F.

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Article abstract of DOI:10.1021/jo00142a015

A facile method has been devised for the synthesis of N-unsubstituted β-lactams.The cis-azido β-lactam (13) obtained by the reaction of azidoacetyl chloride and the Schiff base (10), derived from cinnamaldehyde and a threonine ester, is subjected to contr

Full text of DOI:10.1021/jo00142a015

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