Synthesis of Biotin-containing Peptides Representing the Biotin Binding Site of E. coli Acetyl-CoA Carboxylase

Article abstract of DOI:10.1246/bcsj.55.1579

Two biotin-containing peptides, Ac-Met-Bct-Met-Met-OMe (1) and Boc-Met-Bct-Met-Met, that correspond to the local sequence of biotin carboxyl carrier protein subunit of E. coli acetyl-CoA carboxylase have been synthesized.The precursor tetrapeptide Boc-Met