Journal of Fluorine Chemistry p. 573 - 580 (1982)
Update date:2022-08-02
Topics:
Moores, Ian G.
Smalley, Robert K.
Suschitzky, Hans
2-(Trifluoromethyl)imidazo<4,5-f> and -<4,5-h>quinoline have been prepared from 5(6)-acetamido-2-(trifluoromethyl)benzimidazole and 7,8-diaminoquinoline respectively.These (trifluoromethyl)quinolines like 2-(trifluoromethyl)imidazoles but unlike 2-(trifluoromethyl)benzimidazoles, undergo hydrolysis in dilute sodium hydroxide to give ultimately the corresponding imidazo<4,5-f> and -<4,5-h>quinoline, respectively.
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Doi:10.1016/S0040-4039(00)87391-8
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