CONVERGENT SOLID PHASE PEPTIDE SYNTHESIS. I. SYNTHESIS OF PROTECTED SEGMENTS ON A HYDROXYMETHYLPHENYLOXYMETHYL RESIN USING THE BASE LABILE FMOC α-AMINE PROTECTION. MODEL SYNTHESIS OF LHRH.

DOI: 10.1016/0040-4020(82)85102-8

Source and publish data:

Tetrahedron p. 1183 - 1192 (1982)

Update date:2022-08-03

Topics:

Authors:

Pedroso, E.

Grandas, A.

Saralegui, M. A.

Giralt, E.

Granier, C.

Rietschoten, J. van

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Article abstract of DOI:10.1016/0040-4020(82)85102-8

Convergent solid phase peptide synthesis has been applied to yield LHRH.The segments 1-6 and 7-10 of LHRH were synthesized on a hydroxymethylphenoxymethyl resin using the base labile Fmoc protecting group on the α-amines.The side chains were protected by

Full text of DOI:10.1016/0040-4020(82)85102-8

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