Synthetic Studies in the Indole Series. Preparation of the Unique Antibiotic Alkaloid Chuangxinmycin by a Nitro Group Displacement Reaction

Article abstract of DOI:10.1021/ja00390a037

The total synthesis of the unique sulfur-containing antibiotic indole alkaloid chuangxinmycin is described.This compound, first isolated by Chinese chemists at the Institute of Materia Medica, was assembled from 2,6-dinitrotoluene by a scheme that combine