Synthesis and antibacterial activities of fused pyranoquinoline derivatives

Article abstract of DOI:10.1515/HC.2005.11.3-4.263

Ethyl 2-amino-4-aryl-6-chloro-4-H-pyrano[3,2-h]quinoline-3-carboxylate 1a-e was converted into ethyl 2-(1-pyrrolyl)-4-aryl-6-chloro-4H-pyrano[3,2-h] quinoline-3-carboxylate 2a-e. Several derivatives of the latter compound have been synthesized. Also, the synthesis of 7-aryl-5-chloropyrrolo[1″, 2″:1′,2′]pyrazino[5,6:5′,6′]pyrano- [3,2-h]quinoline and other related heterocycles are described.