Synthesis of (cis-6-Methyltetrahydropyran-2-yl)acetic Acid Involving the Use of an Organoselenium-mediated Cyclization Reaction

DOI: 10.1039/c39820001251

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1251 - 1252 (1982)

Update date:2022-07-30

Topics:

Authors:

Ley, Steven V.

Lygo, Barry

Molines, Huguette

Morton, Judith A.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/c39820001251

A short stereospecific synthesis of (cis-6-methyltetrahydropyran-2-yl) acetic acid (1) has been achieved from readily available starting materials using a novel organoselenium-mediated cyclization of alkenyl-substituted β-oxoesters.

Full text of DOI:10.1039/c39820001251

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:2H-Pyran-6-acetic acid, 3,4-dihydro-2-[(phenylseleno)methyl]-, phenylmethyl ester

Cas No:84885-74-5

R&D Labs maybe for 84885-74-5

zhuzhou zhongle chemical co. ltd.

Contact:+86-0731 28228409

Address:Zhuzhou, Hunan, China
Wuhan Chemchemical Co., Ltd.(expird)

Contact:15973022782

Address:7-5-6218,Incubation Centre,Guandong Industry Park, East Lake High-Tech Development Zone,Wuhan City.
Shandong Yubin Chemical CO.,LTD

website:http://www.yukaichem.com/en.html

Contact:+86-536-8865336

Address:binhai economic development zone，262737 shangdong，china
Jiangsu Allyrise Pharmaceutical Co., Ltd.(expird)

Contact:+86-523-86818997

Address:Taizhou,Jiangsu Province,CHINA
zhangjiagang bonded areas banggao co;ltd

website:http://www.shunchangchem.com

Contact:0086-13921972933

Address:Dongsha Chemical Zone.Zhangjiagang, Jiangsu Province

Relevant to this article

A novel approach to the synthesis of N-substituted 1-C-aminomethyl glycofuranosides

Doi:10.1055/s-2005-922762
(2006)
Multifunctional electron-transporting indolizine derivatives for highly efficient blue fluorescence, orange phosphorescence host and two-color based white OLEDs

Doi:10.1039/c2jm14904d
(2012)
Discovery of a novel series of quinolone and naphthyridine derivatives as potential topoisomerase I inhibitors by scaffold modification

Doi:10.1021/jm900469e
(2009)
Benzothiophenes containing a piperazine side chain as selective ligands for the estrogen receptor α and their bioactivities in vivo

Doi:10.1016/j.bmcl.2004.12.074
(2005)
Allylic alcohol transposition by ortho ester-initiated carbonate extension. Synthesis of the vasodilator 11(R),12(S),15(S)-trihydroxyeicosa-5(Z),8(Z),13(E) -trienoic acid

Doi:10.1021/ol0608808
(2006)
Reaction of dibromoalkanes with silyl phosphites. Synthesis and properties of mono-and diphosphonoalkanes

Doi:10.1134/S1070363206050094
(2006)

Article Doi