Synthesis of (cis-6-Methyltetrahydropyran-2-yl)acetic Acid Involving the Use of an Organoselenium-mediated Cyclization Reaction

DOI: 10.1039/c39820001251

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1251 - 1252 (1982)

Update date:2022-07-30

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Authors:

Ley, Steven V.

Lygo, Barry

Molines, Huguette

Morton, Judith A.

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Article abstract of DOI:10.1039/c39820001251

A short stereospecific synthesis of (cis-6-methyltetrahydropyran-2-yl) acetic acid (1) has been achieved from readily available starting materials using a novel organoselenium-mediated cyclization of alkenyl-substituted β-oxoesters.

Full text of DOI:10.1039/c39820001251

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Product name:2H-Pyran-6-acetic acid, 3,4-dihydro-2-[(phenylseleno)methyl]-, phenylmethyl ester

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