DEALKYLATION OF NUCLEOSIDE ARYLMETHYL 2-CHLOROPHENYL PHOSPHATES: THE 2,4-DINITROBENZYL PROTECTING GROUP

DOI: 10.1016/S0040-4039(00)81574-9

Source and publish data:

Tetrahedron Letters p. 951 - 954 (1983)

Update date:2022-08-04

Topics:

Authors:

Christodoulou, Chris

Reese, Colin B.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)81574-9

Following a study of the effect of benzyl substitution on the rates of nucleophilic dealkylation of phosphotriesters, 2,4-dinitrobenzyl is proposed as a temporary protecting group for 3'-terminal phosphodiester functions in oligonucleotide synthesis.

Full text of DOI:10.1016/S0040-4039(00)81574-9

Products guided by the article

Product name:Phosphoric acid 2-chloro-phenyl ester (2R,3S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-(9-phenyl-9H-xanthen-9-yloxymethyl)-tetrahydro-furan-3-yl ester naphthalen-2-ylmethyl ester

Cas No:84955-55-5

R&D Labs maybe for 84955-55-5

Changzhou Foreign Trade Corp

Contact:+86-519-86623222

Address:29F/D, 99 Yanling West Road, Changzhou, Jiangsu, China
Changsha Botaniex Inc.

Contact:(86) 731 88718666

Address:Room 1222, Unit 4, Building B, Shangcheng, No.47, Kaiyuan East Road.
Jiangxi Hito Chemical Co., Ltd.

Contact:+86-792-3170318

Address:No. 6, Tianhong Ave., Xinghuo Industry Park, Yongxiu, Jiujiang, Jiangxi, China
suzhou BetterBioChem Co., Ltd.

website:http://www.betterbiochem.com

Contact:+86-18013506594

Address:No. 8 Building, 18 nong, Xi Yingnan Road, Pudong, Shanghai,China
Jiangxi Biochem Co.,Ltd

Contact:86-791-86629460

Address:1-6F, 118 Xinzhou road, Nanchang, Jiangxi, China

Relevant to this article

Synthesis of 3-arylpiperazinylalkylpyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as novel, potent, and selective α¹-adrenoceptor ligands

Doi:10.1021/jm040870h
(2005)
OXIDATIVE ADDITION OF ALKANENITRILES TO NICKEL(0) COMPLEXES VIA ?-INTERMEDIATES

Doi:10.1016/S0022-328X(00)98512-7
(1983)
Oxidant controlled Pd-catalysed selective oxidation of primary alcohols

Doi:10.1039/c2cc38086b
(2013)
Synthesis of functionalized α-amino-phosphine oxides and -phosphonates by addition of amines and aminoesters to 4-phosphinyl- and 4-phosphonyl-1,2-diaza-1,3-butadienes

Doi:10.1016/j.tet.2005.01.081
(2005)
Synthesis of a benzolactone collection using click chemistry

Doi:10.1002/ejoc.200600681
(2007)
Design and synthesis of azaisoflavone analogs as phytoestrogen mimetics

Doi:10.1016/j.ejmech.2014.07.030
(2014)

Article Doi