Synthesis and anticancer activity of new pyrrolocarbazoles and pyrrolo-β-carbolines

DOI: 10.1016/j.bmc.2004.12.045

Source and publish data:

Bioorganic and Medicinal Chemistry p. 2263 - 2283 (2005)

Update date:2022-08-04

Topics:

Authors:

Laronze Laronze

Boisbrun

Leonce Leonce

Pfeiffer

Renard Renard

Lozach Lozach

Meijer Meijer

Lansiaux

Bailly Bailly

Sapi Sapi

Laronze Laronze

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Article abstract of DOI:10.1016/j.bmc.2004.12.045

'Bended' 1, 3 or 'linear' 2 pyrrolidino-fused (aza)carbazoles were prepared and screened towards a few cancer-related targets. Whereas 'bended' derivatives 1 and 3 proved to be weakly toxic, several members of the 'linear' family strongly interact with DN

Full text of DOI:10.1016/j.bmc.2004.12.045

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