
Helvetica Chimica Acta p. 612 - 615 (1984)
Update date:2022-08-03
Topics: Synthesis Stereoselective Introduction Steroid Side chains
Wovkulich, Peter M.
Batcho, Andrew D.
Uskokovic, Milan R.
A new short route to chenodeoxycholic acid has been developed.The synthesis is based on the stereoselective introduction of the steroidal side chain via an ene reaction of methyl acrylate and a (17Z)-ethylidene steroid prepared from androstenedione.
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