Bioorganic and medicinal chemistry letters p. 6766 - 6769,4 (2012)
Update date:2022-07-29
Topics:
Juvale, Kapil
Wiese, Michael
We investigated several 2-phenylquinazolines with different substitutions at position 4 for their BCRP inhibition. Compounds with phenyl ring attached via an amine-containing linker at position 4 were found to be potent inhibitors of BCRP. In general compounds with meta substitution of phenyl ring at position 4 were found to have higher inhibitory effect, compound 12 being the most potent and selective towards BCRP.
View MoreYueyang Hudex Pharmaceuticals Ltd.
Contact:0730-8748800
Address:Wujiang Bridge，Yueyang Economy & Technology Development Zone
Beyond Pharmaceutical Co., Ltd
Contact:+86-571-8195-3185
Address:No. 13-1, Liansheng Road, Yuhang District
shanghai Tauto Biotech Co., Ltd
website:http://www.tautobiotech.com/en/index.htm
Contact:+86-21-51320588 ext. 8025
Address:No. 326, Aidisheng Rd , Zhangjiang Hi-tech Park, Shanghai , P.R.CHINA
Contact:+86-15850770348
Address:51 OF XIANGFANGCUN ROAD, Nanjing 210002, China
Contact:86-21 60347964
Address:No.1304, West Meilong Road, Minhang District, Shanghai, China
Doi:10.1021/ja01862a047
(1940)Doi:10.1016/j.bmcl.2020.127411
(2020)Doi:10.1039/b502861b
(2005)Doi:10.1021/jo01136a004
(1952)Doi:10.1016/j.tetlet.2005.04.078
(2005)Doi:10.1038/s41929-021-00661-7
(2021)
