Journal of the American Chemical Society p. 3815 - 3818 (1983)
Update date:2022-09-26
Topics:
Shanzer, Abraham
Samuel, David
Korenstein, Rafi
The design, preparation, and properties of a new series of lipophilic lithium ion carriers are described.The structure of these carriers is based on an acyclic system in which a hexafunctional lipophilic envelope is formed around the metal ion in an octahedral arrangement.The synthesis involves a series of condensation rections using a cyclic tin-oxygen compound as an activated diol precursor.The carrier properties for lithium ions were demonstrated by in vitro experiments on liposomes using a fluorescence assay.The potential pharmacological applications of these ionophores are discussed.
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