Optically active catecholimidazolines: A study of steric interactions at α-adrenoceptors

DOI: 10.1021/jm00361a005

Source and publish data:

Journal of Medicinal Chemistry p. 957 - 963 (1983)

Update date:2022-08-05

Topics:

Authors:

Miller Miller

Hamada Hamada

Craig Craig

Christoph

Gallucci

Rice Rice

Banning Banning

Patil Patil

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Article abstract of DOI:10.1021/jm00361a005

The optical isomers and deoxy form of 2-(3,4,α-trihydroxybenzyl)imidazoline hydrochloride were examined for their α-adrenergic activity on rat aorta. The rank order of stimulant activity was deoxy (2) ? (R)-(-)-1 > (S)-(+)-1. This is in contrast to catech

Full text of DOI:10.1021/jm00361a005

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