Ring-Substituted 1,2-Dialkylated 1,2-Bis(hydroxyphenyl)ethanes. 1. Synthesis and Estrogen Receptor Binding Affinity of 2,2'-and 3,3'-Disubstituted Hexestrols

DOI: 10.1021/jm00362a010

Source and publish data:

Journal of Medicinal Chemistry p. 1137 - 1144 (1983)

Update date:2022-08-04

Topics:

Authors:

Hartmann, Rolf W.

Schwarz, Walter

Schoenenberger, Helmut

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Article abstract of DOI:10.1021/jm00362a010

The syntheses of symmetrically 3,3'- and 2,2'-disubstituted meso hexestrol derivatives are described <3,3'-substituents: OH (1), F (2), Cl (3), Br (4), I (5), CH2N(CH3)2 (6), CH3 (7), CH2OCH3 (8), CH2OC2H5 (9), CH2OH (10), NO2 (11), NH2 (12) N(CH3)2 (13),

Full text of DOI:10.1021/jm00362a010

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