The first total synthesis of (R)-7-butyl-6,8-dihydroxy-3-pentylisochroman- 1-one

Article abstract of DOI:10.1016/j.tetasy.2005.06.003

The enantioselective synthesis of 7-butyl-6,8-dihydroxy-(3R)- pentylisochroman-1-one has been achieved for the first time in which Sharpless asymmetric dihydroxylation is the key step.