Archiv der Pharmazie p. 322 - 328 (2005)
Update date:2022-08-04
Topics:
Lipnicka, Urszula
Regiec, Andrzej
Sulkowski, Emil
Zimecki, Michal
Several new amides 4 of 5-substituted 3-methyl-4-isothiazolecarboxylic acid were obtained. These compounds have acetylamino or benzoylamino groups in position 5 of the isothiazole ring. In position 4, the carboxylic group was transformed in the amides using amino-acid esters. Activities of the obtained derivatives were checked in the humoral immune response and delayed type hypersensitivity reaction to sheep red blood cells (SRBCs) in vivo.
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Doi:10.1021/om050408a
(2005)Doi:10.1021/om060007a
(2006)Doi:10.1016/j.tet.2005.07.081
(2005)Doi:10.1002/ejoc.200500143
(2005)Doi:10.1021/jo01373a014
(1954)Doi:10.1021/ol051221i
(2005)
