Mitomycin C Analogues with Secondary Amines at Position 7

DOI: 10.1021/jm00364a018

Source and publish data:

Journal of Medicinal Chemistry p. 1453 - 1457 (1983)

Update date:2022-07-30

Topics:

Authors:

Iyengar, Bhashyam S.

Sami, Salah M.

Tarnow, Shirley E.

Remers, William A.

Bradner, William T.

Schurig, John E.

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Article abstract of DOI:10.1021/jm00364a018

A series of mitomycin C analogues with secondary amines at position 7 was prepared from mitomycin A.Eleven of the 20 new compounds in this series were more active than mitomycin C against P-388 murine leukemia, and 2 of these 11 were significantly less le

Full text of DOI:10.1021/jm00364a018

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