Synlett p. 2080 - 2082 (2005)
Update date:2022-07-30
Topics:
Lomberget, Thierry
Radix, Sylvie
Barret, Roland
The synthesis of 4,7-dimethoxy 5- and 6-azaindoles, a structural unit that is present in recently developed anti-HIV-1 agents, was achieved in a regioselective manner. The developed strategy is based on the appropriate choice of a protecting group during a lithium-mediated formylation step, followed by thermal cyclization of azidoacrylates. Georg Thieme Verlag Stuttgart.
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