CONVENIENT METHOD FOR THE SYNTHESIS OF ADENYLYL-(2 prime - 5 prime )-ADENYLYL-(2 prime - 5 prime )-ADENOSINE USING 3 prime -O-BENZOYLADENOSINE DERIVATIVES.

Article abstract of DOI:10.1246/bcsj.56.1424

N**6,3 prime -O-Dibenzoyladenosine was prepared by treating 2 prime ,3 prime -0-(dibutylstannylene)-N**6-benzolyladenosine with benzoyl chloride in methanol. The trimeric adenylyl-(2 prime - 5 prime k)-adenylyl-(2 prime - 5 prime )-adenosine was synthesized in a good yield using N**6,3 prime - O-dibenzoyladenosine as the starting material via the phosphotriester approach.