Specificity of extended O-aryloxycarbonyl hydroxamates as inhibitors of a class C β-lactamase

DOI: 10.1016/j.bmc.2019.02.023

Source and publish data:

Bioorganic and Medicinal Chemistry p. 1430 - 1436 (2019)

Update date:2022-08-05

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Authors:

Malico, Alexandra A.

Dave Dave

Adediran

Pratt Pratt

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Article abstract of DOI:10.1016/j.bmc.2019.02.023

Class C β-lactamases have previously been shown to be efficiently inactivated by O-aryloxycarbonyl hydroxamates. O-Phenoxycarbonyl-N-benzyloxycarbonylhydroxylamine (1) and O-phenoxycarbonyl-N-(R)-[(4-amino-4-carboxy-1-butyl)oxycarbonyl]hydroxylamine (2),

Full text of DOI:10.1016/j.bmc.2019.02.023

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