Synthesis and antiviral activity of 7-deazaneplanocin a against orthopoxviruses (vaccinia and cowpox virus)

DOI: 10.1016/j.bmcl.2005.10.007

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 285 - 287 (2006)

Update date:2022-07-30

Topics:

Authors:

Arumugham, Balakumar

Kim, Hyo-Joong

Prichard, Mark N.

Kern, Earl R.

Chu, Chung K.

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Article abstract of DOI:10.1016/j.bmcl.2005.10.007

An efficient method for the synthesis of 7-deazaneplanocin A (2) has been accomplished by the condensation of cyclopentenol 3 with 6-chloro-7-deazapurine followed by subsequent functional group manipulations. The synthesized 7-deazaneplanocin A (2) exhibi

Full text of DOI:10.1016/j.bmcl.2005.10.007

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Product name:7-((3aS,4R,6aR)-6-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyl-3a,6a-dihydro-4H-cyclopenta[d][1,3]dioxol-4-yl)-4-chloro-7H-pyrrolo[2,3-d]pyrimidine

Cas No:873203-07-7

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