Kinetics of Decarboxylation of the Two Epimers of 5-tert-Butyl-1-methyl-2-oxocyclohexanecarboxylic Acid: Lack of Stereoelectronic Control in β-Keto Acid Decarboxylation

DOI: 10.1021/jo00172a011

Source and publish data:

Journal of Organic Chemistry p. 4497 - 4502 (1983)

Update date:2022-08-05

Topics:

Authors:

Kayser, Robert H.

Brault, Margaret

Pollack, Ralph M.

Bantia, Shanta

Sadoff, Scott F.

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Article abstract of DOI:10.1021/jo00172a011

Rates of decarboxylation of the two epimers of 5-tert-butyl-1-methyl-2-oxocyclohexanecarboxylic acid have been measured under both acidic and basic conditions at 25 deg C.The decomposition of isomer 1e (methyl and tert-butyl trans) is more rapid than that

Full text of DOI:10.1021/jo00172a011

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