SYNTHESIS OF 1-ARYL-3-(3-PYRROLYL)-5-OXOPYRAZOLES

DOI: 10.1007/BF00516451

Source and publish data:

Chemistry of Heterocyclic Compounds p. 863 - 867 (1983)

Update date:2022-08-02

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Authors:

Zhestkov, V.P.

Voronin, V.G.

Portnov, Yu.N.

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Article abstract of DOI:10.1007/BF00516451

1-Aryl-3-(2,4-dimethyl-5-ethoxycarbonyl-3-pyrrolyl)-5-oxopyrazoles were obtained by condensation of ethyl β-(2,4-dimethyl-5-ethoxycarbonyl-3-pyrrolyl)-β-ketopropionate with arylhydrazines.Electron-donor substituents in the aromatic ring of the arylhydrazines accelerate the cyclization of the intermediate hydrazones, whereas electron-acceptor substituents hinder cyclization.

Full text of DOI:10.1007/BF00516451

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