Synthesis of a new potent anti-ulcer and gastric secretory inhibiting agent, (-)-cis-2,3-dihidro-3-(4-methylpiperazinylmethyl)-2-phenyl-1,5-benzothiaze pin-4(5H)-one hydrochloride (BTM-1086), and related compounds

DOI: 10.1248/cpb.31.1780

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1780 - 1783 (1983)

Update date:2022-08-05

Topics:

Authors:

Ohno Ohno

Izumi Izumi

Mizukoshi

Kato Kato

Hori Hori

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.31.1780

(-)-cis-2,3-Dihydro-3-(4-methylpiperazinylmethyl)-2-phenyl-1,5-benzothiazepin-4(5H)-one hydrochloride (BTM-1086) and its analogues, which possessed potent anti-ulcer and gastric secretory inhibiting activities, were synthesized and the structure of these compounds were established on the basis of spectral and chemical evidences.

Full text of DOI:10.1248/cpb.31.1780

NII-Electronic Library Service

Products guided by the article

Product name:2-[(2-Amino-phenylsulfanyl)-(4-chloro-phenyl)-methyl]-malonic acid diethyl ester

Cas No:87707-90-2

R&D Labs maybe for 87707-90-2

Guangzhou PI & PI Biotech Inc. Ltd.

Contact:+86-20-81716320

Address:13th Floor, Xinbao Technology Industrial Park, No. 2 Ruixiang Road, Huangpu District, Guangzhou,Guangdong,China
Shanghai UCHEM Inc.

Contact:+86-21-56338808

Address:799 Dunhuang Road, Putuo
Hybio Pharmaceutica Co.,Ltd

Contact:+86 755 26588093

Address:No.9 Linkong West Street, Hengdian Street, Huangpi District, Wuhan City, China.
Zhaodu Fine Chemical Plant

Contact:86-310-8067016

Address:East Fuhua Road,Tiexi Chemical Industrial Estate,Hebei,China
Hubei Onward Bio-Development Co., Ltd.

Contact:+86-718-8417012

Address:No.517,Shizhou Avenue,Enshi City,Hubei Province,China,445002

Relevant to this article

Convenient and Stereospecific Synthesis of Deoxy Sugars. Reductive Displacement of Trifluoromethanesulfonates

Doi:10.1021/jo00175a040
(1984)
Doi:10.1039/jr9480000381
(1948)
Fluorescent iridium(iii) coumarin-salicylaldehyde Schiff base compounds as lysosome-targeted antitumor agents

Doi:10.1039/d0dt00627k
(2020)
Potent 4-arylalkyl-substituted 3-isothiazolol GABA_A competitive/noncompetitive antagonists: Synthesis and pharmacology

Doi:10.1021/jm050987l
(2006)
Non-redox-assisted oxygen-oxygen bond homolysis in titanocene alkylperoxide complexes: [Cp₂Ti^IV(η¹-OO ^tBu)L]^+/0, L = Cl^-, OTf^-, Br ^-, OEt₂, et₃P

Doi:10.1021/om050818z
(2006)
Chemical properties of 4,5-di(ethoxycarbonyl)-1,3-dioxolan-2-yl (DECDO) as a hydroxyl protecting group of the 2′-hydroxyl function in ribonucleosides

Doi:10.1002/jhet.5570440208
(2007)

Article Doi