
Chemical and Pharmaceutical Bulletin p. 1780 - 1783 (1983)
Update date:2022-08-05
Topics:
Ohno
Izumi
Mizukoshi
Kato
Hori
(-)-cis-2,3-Dihydro-3-(4-methylpiperazinylmethyl)-2-phenyl-1,5-benzothiazepin-4(5H)-one hydrochloride (BTM-1086) and its analogues, which possessed potent anti-ulcer and gastric secretory inhibiting activities, were synthesized and the structure of these compounds were established on the basis of spectral and chemical evidences.
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