Synthesis of a new potent anti-ulcer and gastric secretory inhibiting agent, (-)-cis-2,3-dihidro-3-(4-methylpiperazinylmethyl)-2-phenyl-1,5-benzothiaze pin-4(5H)-one hydrochloride (BTM-1086), and related compounds

DOI: 10.1248/cpb.31.1780

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1780 - 1783 (1983)

Update date:2022-08-05

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Authors:

Ohno Ohno

Izumi Izumi

Mizukoshi

Kato Kato

Hori Hori

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Article abstract of DOI:10.1248/cpb.31.1780

(-)-cis-2,3-Dihydro-3-(4-methylpiperazinylmethyl)-2-phenyl-1,5-benzothiazepin-4(5H)-one hydrochloride (BTM-1086) and its analogues, which possessed potent anti-ulcer and gastric secretory inhibiting activities, were synthesized and the structure of these compounds were established on the basis of spectral and chemical evidences.

Full text of DOI:10.1248/cpb.31.1780

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