Electrophilic aromatic fluorination with fluorine: meta-Directed fluorination of anilines

DOI: 10.1016/j.jfluchem.2005.02.013

Source and publish data:

Journal of Fluorine Chemistry p. 661 - 667 (2005)

Update date:2022-08-04

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Authors:

Alric Alric

Marquet Marquet

Billard Billard

Langlois

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Article abstract of DOI:10.1016/j.jfluchem.2005.02.013

Anilines are mainly or selectively fluorinated in the meta-position with F₂ when dissolved in triflic acid, sometimes in the presence of small quantities of antimony pentafluoride. The regioselectivity is increased when an electron-donating substituent is present at the para-position.

Full text of DOI:10.1016/j.jfluchem.2005.02.013

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