Bond Fixation in Annulenes. 15. A Titanium(0)-Mediated Synthesis of a Cyclooctatetraene. Probe of the Relative Size of the Interstitial Phenyl Substituent in 1,3-Dimethyl-2-phenylcyclooctatetraene by means of Racemization Kinetics

Article abstract of DOI:10.1021/ja00364a030

A fully regiospecific synthesis of racemic 1,3-dimethyl-2-phenylcyclooctatetraene (23a) has been achieved on the basis of the expectation that trans-4-methyl-5-acetyl-4-cyclohexenyl phenyl ketone (21a) would undergo efficient titanium(0)-promoted cyclizat