Synthesis and biological characterization of [3H] (2-amino-4,5,6,7-tetrahydrobenzo[b]thiophen-3-yl)-(4-chlorophenyl)-methanone, the first radiolabelled adenosine A1 allosteric enhancer

Article abstract of DOI:10.1016/j.bmcl.2005.11.037

Among the adenosine A₁ allosteric enhancers reported so far, compound (2-amino-4,5,6,7-tetrahydrobenzo[b]thiophen-3-yl)-(4-chlorophenyl)- methanone 1 (named T-62) has shown biological properties similar to those of PD 81,723, the reference A