Rapid generation of molecular complexity using "hybrid" multi-component reactions (MCRs): Application to the synthesis of α-amino nitriles and 1,2-diamines

Article abstract of DOI:10.1039/b516192d

Methyleneaziridines can be converted into a wide range of 1,2-diamines and 2-cyanopiperidines in a single operation with the formation of three intermolecular carbon-carbon bonds using a "hybrid" MCR. The Royal Society of Chemistry 2006.