REACTION OF PHOSPHORUS PENTACHLORIDE WITH PERHALO CARBONYL-CONTAINING COMPOUNDS

Article abstract of DOI:10.1016/S0022-1139(00)83930-5

The reaction between PCl5 and the carbonyl oxygen in a variety of perfluoro compounds containing the carbonyl functional group, e.g.R_fC(O)R'_f, R_fC(O)X or XC(O)R_fC(O)X, where X = Cl, F, OH, NH2, and ONH4 has led to a convenient synthesis procedure for fluorochlorocompounds.Monoketones, e.g.R_fC(O)R'_f, yield R_fCCl2R'_f compounds, while the diketones, e.g.R_fC(O)(CF2)nC(O)R'_f, also react to yield the fluorochloro compounds.When n = 3, R_fCCl2(CF2)3CCl2R'_f is produced in quite high yields (65 percent); however, when n = 2, the principal product is a cyclic fluorodichloroether compound while the fluorotetrachloro compound is the minor product.The R_fC(O)X and XC(O)R_fC(O)X compounds produce R_fCCl3 and Cl3CR_fCCl3 respectively in high yields.Reaction temperature and pressure are important factors for high yield synthesis.