ASYMMETRIC REDUCTION OF α,β-UNSATURATED KETONES WITH CHIRAL HYDRIDE REAGENTS PREPARED FROM LITHIUM ALUMINIUM HYDRIDE AND (S)-4-ANILINO- AND (S)-4-(2,6-XYLIDINO)-3-METHYLAMINO-1-BUTANOL

Article abstract of DOI:10.1016/S0040-4039(00)88278-7

The asymmetric reduction of prochiral α,β-unsaturated ketones with chiral hydride reagents derived from lithium aluminium hydride and (S)-4-(2,6-xylidino)-3-methylamino-1-butanol gives (S)- and (R)-allylic alcohols in high chemical and optical yields, respectively.