5-Aryl-3-azabicycloheptan-6-one Ketals, Compounds with Morphine-Like Analgesic Activity

DOI: 10.1021/jm00371a012

Source and publish data:

Journal of Medicinal Chemistry p. 628 - 632 (1984)

Update date:2022-08-05

Topics: Ketals

Authors:

McKenzie, Thomas C.

Epstein, Joseph W.

Fanshawe, William J.

Dixon, J. Scott

Osterberg, Arnold C.

et al. et al.

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Article abstract of DOI:10.1021/jm00371a012

A series of 5-aryl-3-azabicyclo<3.2.0>heptan-6-one ketals 6 were synthesized by hydride reduction of 1-aryl-4,4-dimethoxy-1,2-cyclobutanedicarboximides 5.Imides 5 were obtained as the sole, regioselective products of the <2 + 2> photocycloaddition of 1,1-

Full text of DOI:10.1021/jm00371a012

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