Studies in biomimetic alkaloids syntheses - 9. Two total syntheses of minovincine

Article abstract of DOI:10.1016/S0040-4020(01)88609-9

Condensation of methyl 1,2,3,4,5,6-hexahydroazepino[4,5-b]indole-5-carboxylate with the ethylene ketal of 2-acetyl-5-chloropentanal, followed by reactions with triethylamine and aqueous acid gave minovincine. Alternatively, a condensation of the indoloaze