Journal of Medicinal Chemistry p. 4269 - 4274 (2006)
Update date:2022-08-03
Topics:
McLean, Thomas H.
Chambers, James J.
Parrish, Jason C.
Braden, Michael R.
Marona-Lewicka, Danuta
Kurrasch-Orbaugh, Deborah
Nichols, David E.
A conformationally restricted analogue of mescaline, C-(4,5,6- trimethoxyindan-1-yl)-methanamine, was designed using a 5-HT2A receptor homology model. The compound possessed 3-fold higher affinity and potency than and efficacy equal to that of
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