Synthesis of stereochemical probes for new fluorogenic assays for yeast transketolase variants

DOI: 10.1016/j.tet.2006.02.033

Source and publish data:

Tetrahedron p. 3969 - 3976 (2006)

Update date:2022-07-29

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Authors:

Sevestre, Aurélie

Charmantray, Franck

Hélaine, Virgil

Lásiková, Angelika

Hecquet, Laurence

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Article abstract of DOI:10.1016/j.tet.2006.02.033

For the screening of yeast transketolase (TK) variants with improved or new properties acquired by random mutagenesis, we report on the stereoselective synthesis of fluorogenic substrates as probes for measuring TK activity. Compound 1 (7-(2′,3′,5′-trihyd

Full text of DOI:10.1016/j.tet.2006.02.033

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