The synthesis of one enantiomer of the α-methyl-trans-cyclopropane unit of mycolic acids

Article abstract of DOI:10.1016/j.tet.2006.03.007

We report the synthesis of a single enantiomer of an α-methyl-trans-cyclopropane unit present in a number of mycolic acids and its incorporation into a reported 1,2-dialkylcyclopropane meromycolate that contains one cis-1,2-dialkylcyclopropane and one α-methyl-trans-1,2-dialkylcyclopropane.