
Chemistry of Heterocyclic Compounds p. 1202 - 1207 (1983)
Update date:2022-08-04
Topics:
Krauze, A. A.
Kalme, Z. A.
Pelcher, Yu. E.
Liepin'sh, E. E.
Dipan, I. V.
Dubur, G. Ya.
3-Cyano-4,6-diaryl-3,4-dihydropyridine-2-thiones have been synthesized for the first time by the condensation of arylideneacetophenones or 1-piperidino-1-phenyl-2-benzoylethane with cyanothioacetamide and the 1,1-dicyano-2-aryl-3-benzoylpropane with hydrogen sulfide in the presence of bases.It has been established by PMR spectroscopy that 3-cyano-3,4-dihydropyridine-2-thiones exist in solutions in the form of mixture of cis and trans isomers.
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Doi:10.1039/jm9960600919
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