Chemical and Pharmaceutical Bulletin p. 247 - 255 (1995)
Update date:2022-08-04
Topics:
Seki
Takezaki
Ohuchi
Ohuyabu
Tanimoto
Yamaguchi
Saitoh
Ishimori
Yasuda
A series of phenoxypropanolamines having a hydrazinopyridazinyl moiety was synthesized. Their hypotensive and β-blocking activities were evaluated after intravenous administration of the compounds to anesthetized rats. Some of them exhibited both activities. In particular, compound 20k is a candidate for clinical use due to its hypotensive activity, equal to that of hydralazine, and its β-blocking activity, 2.7-fold more potent than that of propranolol.
View Morewebsite:http://www.tcfinechem.com/
Contact:18681346930
Address:baifu town,whou district
Anhui Gusheng Import&Export CO.,LTD
Contact:86-551-63662296
Address:Jinzhai Road NO.162 ,hefei, china
Wuhan Chemchemical Co., Ltd.(expird)
Contact:15973022782
Address:7-5-6218,Incubation Centre,Guandong Industry Park, East Lake High-Tech Development Zone,Wuhan City.
Shanghai Bosman Industrial Co., Ltd
Contact:86-21-63065878-8006
Address:Rm907, No.1611, North Sichuan Road, Hongkou District, Shanghai, 200080 China
Shandong Xinke Petrochemical Co., Ltd.
Contact:+86-546-7277016
Address:Gudao Industrial Park, Hekou District, Dongying, Shandong Province, China
Doi:10.1021/ic060111k
(2006)Doi:10.1016/S0040-4039(00)88392-6
(1983)Doi:10.1248/cpb.53.492
(2005)Doi:10.1021/jm051263c
(2006)Doi:10.1016/j.tetlet.2006.03.175
(2006)Doi:10.1021/jo980451q
(1998)
