A regioselective synthesis of 3-benzazepinones via intramolecular hydroamidation of acetylenes

Article abstract of DOI:10.1016/j.tetlet.2006.03.198

Synthesis of 3-benzazepinones by palladium-catalyzed intramolecular addition of amides to alkynes is achieved. Phenyl acetylenes substituted in the ortho-position with tethered amide functionality were prepared in a few steps from readily available starti