Preparation of antibodies against a novel immunosuppressant, FTY720, and development of an enzyme immunoassay for FTY720

DOI: 10.1016/j.bmc.2006.01.071

Source and publish data:

Bioorganic and Medicinal Chemistry p. 4182 - 4192 (2006)

Update date:2022-08-05

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Authors:

Matsumoto, Norimasa

Kohno, Takeyuki

Uchida, Shuji

Shimizu, Takaaki

Kusumoto, Haruko

Hirose, Ryoji

Yanada, Kazuo

Kurio, Wasako

Yamaguchi, Shoji

Watabe, Kazuhito

Fujita, Tetsuro

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Article abstract of DOI:10.1016/j.bmc.2006.01.071

FTY720 (1) is a novel immunosuppressant (immunomodulator), derived from ISP-I (2: myriocin and thermozymocidin). To clarify the pharmacokinetic properties of 1, antibodies against 1 were prepared and a competitive enzyme immunoassay (EIA) was developed. T

Full text of DOI:10.1016/j.bmc.2006.01.071

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